As Week 16 of the NFL season approaches, divisional matchups become crucial for betting strategies. The Philadelphia Eagles face the Washington Commanders, where a win or tie could clinch the NFC East title for the Eagles. Philadelphia is favored by 3.5 points, with a total points over/under of 45.5.

Recent trends show the Eagles have dominated the Commanders, winning six of their last seven meetings. However, the Commanders have been strong against the spread at home. Other notable matchups include the Titans vs. Colts and Lions vs. Bears, with various betting insights available.